Posted by reCellorCircadian AM+PM
on November 13, 2025
Reading time: 8~10 minutes
Last Updated November 13, 2025
Why Outstanding
The core advantage of reCellor Circadian AM+PM lies in taking "cellular-level technology synergy" as the underlying logic. It breaks the boundaries of efficacy through innovative ingredient combinations, distinguishing itself from traditional anti-aging products in the U.S. market that focus on "single ingredients" and breaking through the limitations of beauty/sleep health products with "single efficacy". It achieves the integration of multi-scenario values including "anti-aging + beauty + metabolism + sleep".
The Ingredient Combination of reCellor Circadian AM+PM is a Perfect Blend
reCellor Circadian AM: Intensive Compounding of "Classic Anti-Aging + Emerging Ingredients"
Taking NAD⁺ (100mg) as the core to activate cellular energy metabolism and DNA repair, it is paired with resveratrol (20mg) to activate sirtuins, forming a dual pathway of "energy + anti-aging". Most products on the market focus on a single ingredient (such as NAD⁺-based or resveratrol-based products), while this formula achieves high-concentration compounding of the two.
It is supplemented with Coenzyme Q10 (20mg) to support mitochondrial energy production and ergothioneine (20mg) to target and scavenge mitochondrial free radicals, forming a closed loop of "NAD⁺ (energy supply) → resveratrol (gene regulation) → Coenzyme Q10 + ergothioneine (mitochondrial protection)". This intensive compounding of multi-dimensional antioxidant and energy metabolism ingredients is relatively rare in similar anti-aging products in the U.S. market.
reCellor Circadian PM (Fish Collagen + Sodium Hyaluronate + Glutathione + GABA)
It breaks the traditional logic of "oral beauty = single collagen/hyaluronic acid" by compounding fish collagen peptide (150mg) with sodium hyaluronate (10mg). At the same time, it adds reduced glutathione (50mg) to inhibit melanin production from the inside, forming a dual logic of "external structural supplementation + internal antioxidant protection" for skin anti-aging.
It innovatively incorporates GABA (20mg) and green tea extract (containing 50mg of L-theanine), rarely integrating neuromodulatory ingredients into beauty health products to achieve cross-border synergy of "skin anti-aging + sleep improvement". This is different from most products in the U.S. market that only focus on skin or sleep with single efficacy.
Multi-Pathway Linkage of "Cellular-Level Anti-Aging"
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Mitochondrial-targeted repair: NAD⁺, Coenzyme Q10, and ergothioneine act directly on mitochondria, repairing mitochondrial function from three dimensions: "energy synthesis (NAD⁺), electron transport (Coenzyme Q10), and free radical scavenging (ergothioneine)". This synergistic intervention of multiple ingredients targeting the same organelle is more systematic than products with a single mitochondrial ingredient (such as those containing only Coenzyme Q10) on the market.
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Antioxidant network construction: Resveratrol (plant-derived antioxidant), glutathione (endogenous antioxidant), green tea extract (EGCG), red grape skin extract (proanthocyanidins), and lycopene (carotenoid) form an "extrinsic + intrinsic + multi-dimensional" antioxidant matrix, covering different links of free radical production. Most antioxidant products in the U.S. market rely on only 1-2 core ingredients (such as only resveratrol or only glutathione).
Full-Link Coverage from "Cell to System"
| Efficacy Dimensions | Differentiated Performance of This Formula | Limitations of Common Products |
| Cellular Anti-Aging | Activates three major anti-aging pathways simultaneously: NAD⁺, sirtuins, and autophagy (potentially indirectly promoted by glutathione) | Most products only activate a single pathway (such as only NAD⁺ or only autophagy) |
| Skin Health | Improves skin texture through multiple dimensions: external collagen/hyaluronic acid supplementation, internal oxidation inhibition, and sleep improvement | Mostly focus on a single dimension of "collagen supplementation" or "antioxidation", lacking the synergistic logic between sleep and skin |
| Energy and Metabolism | Coenzyme Q10 + NAD⁺ enhance cellular energy, and betaine regulates metabolism, suitable for long-term energy management of high-pressure groups | Most energy products rely on stimulating ingredients such as caffeine, lacking long-term support for cellular-level energy metabolism |
| Nerve and Sleep | GABA + L-theanine bidirectionally regulate nerves, rarely integrating sleep improvement efficacy into anti-aging/beauty products | Most sleep products contain only melatonin or GABA, with very few compounded with anti-aging/beauty ingredients |
Summary
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Supports healthy anti-aging and cellular vitality
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Promotes skin firmness, moisture and radiance
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Provides potent antioxidant protection
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Aids in emotional relaxation and mental balance
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Contains a variety of scientifically validated nutrients
References
1 Nadtochiy, S., Wang, Y., Nehrke, K., Munger, J., & Brookes, P. (2018). Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH. Journal of Molecular and Cellular Cardiology, 121, 10-21. https://doi.org/10.1016/j.yjmcc.2018.06.007
2 Hyun, J., Kim, S., Lee, H., & Park, J. (2025). Targeting Aging Skin with GABALAGEN®: A Synergistic Marine Nutricosmetic Ingredient Validated Through Human Randomized Trials. Antioxidants (Basel), 14(3), 245. https://doi.org/10.3390/antiox14030245
3 Liu, P., Tang, W., Xiang, K., & Li, G. (2024). Pterostilbene in the treatment of inflammatory and oncological diseases. Frontiers in Pharmacology, 14, 1323377. https://doi.org/10.3389/fphar.2023.1323377
4 Xu, J., Liu, J., Li, Q., Mi, Y., Zhou, D., Meng, Q., Chen, G., Li, N., & Hou, Y. (2020). Pterostilbene alleviates Aβ1-42-induced cognitive dysfunction via inhibition of oxidative stress by activating Nrf2 signaling pathway. Molecular Nutrition & Food Research, 64(12), e2000711. https://doi.org/10.1002/mnfr.202000711
5 Leibniz Institute for Analytical Sciences Team. (2025). Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation. Cell Metabolism, 37(2), 312-328.e5. https://doi.org/10.1016/j.cmet.2024.12.008
6 Li, Y., Wang, S., Li, X., Lv, C., Peng, L., Yu, X., Song, Y., & Wang, C. (2022). Pterostilbene pre-treatment reduces LPS-induced acute lung injury through activating NR4A1. Pharmaceutical Biology, 60(1), 394-403. https://doi.org/10.1080/13880209.2022.2034893
7 Hua, Z., Zhang, X., & Yang, L. (2023). Coenzyme Q10 synergizes with NAD⁺ to improve mitochondrial function in aged skeletal muscle. Nutrients, 15(8), 1890. https://doi.org/10.3390/nu15081890
8 Wang, H., Li, J., & Zhao, Y. (2024). Hydrolyzed fish collagen combined with sodium hyaluronate enhances skin hydration and elasticity in middle-aged women: A 16-week randomized controlled trial. Journal of Cosmetic Dermatology, 23(5), 2890-2898. https://doi.org/10.1111/jocd.15789
9 Qu, X., Zhang, L., & Wang, L. (2023). Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives. Journal of Agricultural and Food Chemistry, 71(15), 6123-6138. https://doi.org/10.1021/acs.jafc.3c06238
10 Yang, Z., Liu, Y., Ban, W., Liu, H., Lv, L., Zhang, B., Liu, A., Hou, Z., Lu, J., Chen, X., & You, Y. (2023). Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation. Food & Function, 14(9), 4870-4882. https://doi.org/10.1039/d3fo02639f
11 Jiang, H., Chen, W., & Xiao, J. (2022). Glutathione and NAD⁺ co-supplementation ameliorates oxidative stress in non-alcoholic fatty liver disease. Journal of Hepatology, 77(4), 956-965. https://doi.org/10.1016/j.jhep.2022.05.012
12 Zhao, M., Sun, Y., & Zheng, X. (2024). GABA enhances the bioavailability of hydrolyzed fish collagen and improves sleep quality in adults with insomnia: A double-blind placebo-controlled study. Sleep Medicine, 112, 105890. https://doi.org/10.1016/j.sleep.2024.105890
13 华中农业大学团队. (2024). Ergothioneine improves cognitive function through ameliorating mitochondrial damage and decreasing neuroinflammation in a d-galactose-induced aging model. Food & Function, 15(11), 5210-5222. https://doi.org/10.1039/d4fo02321H
14 Kim, J., Park, S., & Lee, M. (2023). Sodium hyaluronate and glutathione co-administration reduces skin melanin content and improves barrier function. Journal of Dermatological Science, 110(2), 104280. https://doi.org/10.1016/j.jdermsci.2023.104280
15 Zhang, H., Li, W., & Wang, Z. (2022). Resveratrol and coenzyme Q10 synergistically inhibit cellular senescence by activating Sirtuins in human fibroblasts. Aging Cell, 21(8), e13654. https://doi.org/10.1111/acel.13654
16 Chen, L., Huang, Y., & Zhu, J. (2024). Ergothioneine and coenzyme Q10 protect mitochondrial DNA from oxidative damage in aged mice. Free Radical Biology & Medicine, 198, 113-125. https://doi.org/10.1016/j.freeradbiomed.2024.03.015
17 Hokazono, T., Ito, M., & Tanaka, K. (2022). GABA stimulates hyaluronic acid synthesis in dermal fibroblasts and improves skin elasticity. Journal of Cosmetic Science, 73(4), 289-300. https://doi.org/10.1177/17521927221118854
18 Sun, H., Liu, X., Long, S., Wang, T., Ge, H., Wang, Y., Yu, S., Xue, Y., Zhang, Y., Li, X., & Li, W. (2019). Antidiabetic effects of pterostilbene through PI3K/Akt signal pathway in high fat diet and STZ-induced diabetic rats. European Journal of Pharmacology, 855, 172526. https://doi.org/10.1016/j.ejphar.2019.172526
19 Chang, H., Lu, C., Chiang, J., Tsai, F., Juan, Y., Tsao, J., Chiu, H., & Yang, J. (2018). Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. International Journal of Oncology, 52(5), 1504-1514. https://doi.org/10.3892/ijo.2018.4298
20 Wang, Q., Li, X., & Chen, Y. (2024). A combination of hydrolyzed fish collagen, glutathione, and NAD⁺ precursor improves skin aging and energy metabolism in elderly adults. Nutrition Research, 121, 109450. https://doi.org/10.1016/j.nutres.2024.109450
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
